tert-Butylhydroquinone CAS NO.1948-33-0

Amide is a very weak base, it can be alcoholized with strong acids, and the adduction formed by the reaction, such as CH3CONH2·HCl, is very unstable and completely hydrolyzed in water. Amides can also form metal salts, most metal salts are completely hydrolyzed when they meet water, but mercury salts (CH3CONH) 2Hg are quite stable. Amides are heated for a long time in the presence of strong acids and bases and can be hydrolyzed into carboxylic acids and ammonia (or amines). The amide is carefully heated in the presence of the dehydrating agent phosphorus pentoxide to convert to nitrile. Amide can be reduced to amine by catalytic hydrogenation or reaction with lithium aluminum hydride. An amide can also react with a subhalide to form a primary amine with one less carbon atom. Amides can be prepared by partial dehydrating of carboxylate ammonium salts, or by ammonolysis of acyl halides, anhydrides, and esters. Nitrile can also be partially hydrolyzed, stopping at the amide stage. Low molecular weight liquid amides such as N, N-dimethylformamide, N, N-dimethylacetamide are excellent aprotic polar solvents, and can also be used as plasticizers, lubricating oil additives and organic synthesis reagents.

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